KS3 · Biology

Gametes and fertilisation

You started life as one cell with 46 chromosomes, yet your mum's egg and your dad's sperm had only 23 each. How does that add up?

The human life cycle

Rebuild the loop, and follow the chromosome number

3 stages are missing. Use the rest of the loop to work out which goes where.

  1. Stage 1: Adult

    The cells of the body have 46 chromosomes. Adults are the ones who make gametes.

  2. Stage 3: Fertilisation

    The nucleus of a sperm fuses with the nucleus of an egg. The new nucleus gets 23 chromosomes from each parent, so it has 46 again.

  3. Stage 5: Embryo

    The zygote divides into a ball of cells. Every new cell has 46 chromosomes.

  4. Stage 7: Baby

    Ready to be born. The baby has 46 chromosomes too.

  5. Stage 8: Child, then adolescent

    More growth, which means making new cells, until the person is an adult and the loop can start again.

…and stage 8 leads back to stage 1.

Fertilisation, step by step

Step through what happens when a sperm cell meets an egg cell.

Which idea sounds right to you?

Three ideas that sound sensible and are not

A baby is born. Where did its genetic material come from, and how many chromosomes are involved?

Which of these is closest to what you think right now?
How sure are you?

Does the rule work for a horse?

The halving rule is not just for humans. Commit to an answer before you reveal it.

An adult horse has 64 chromosomes in the nuclei of its body cells. How many chromosomes will there be in one horse sperm cell, in one horse egg cell, and in the foal that results?

Write it in your own words

Describe the role of gametes and fertilisation

Describe the role of gametes and fertilisation in human reproduction. [4 marks]

0 words · your answer stays on this page and is not sent anywhere.

WHAT YOU'VE LEARNED

A quick recap of today's lesson.

What you need to know

  • Gametes are sex cells: the sperm cell is the male gamete and the egg cell is the female gamete.
  • Each gamete carries half the genetic material. In humans that is 23 chromosomes in each gamete, against 46 in the body cells.
  • Fertilisation happens when the nucleus of a sperm fuses with the nucleus of an egg, in a fallopian tube, to form a zygote.
  • The zygote divides into an embryo, then a foetus grows in the uterus, then a baby is born. Everything after the zygote is growth.

The big picture

Humans are made when two special cells, a sperm and an egg, fuse. Each of these gametes carries half the genetic material (23 chromosomes), so the zygote they make has the full 46, half from each parent. The zygote then grows through embryo, foetus and baby.

Key points

1Humans reproduce sexually, so half of a baby's genetic material comes from each parent.
2DNA is a long chemical molecule that is packaged into chromosomes, and the chromosomes are stored in the nucleus.
3Gametes have half the number of chromosomes of the parent. Offspring have the same number as their parents.
4Fertilisation takes place in the fallopian tube, before the egg reaches the uterus.
5In the life cycle, reproduction is the step from adult to zygote. Every stage after that is growth, which is making new cells.
6Different species have different numbers of chromosomes, and the number has nothing to do with how complicated the species is.

Worked example

Problem

A clownfish has 24 chromosomes in the nuclei of its body cells. How many chromosomes are in one clownfish sperm cell, and how many are in a baby clownfish's body cells?

⚠ Watch out

Mixing up what a gamete carries and what the zygote carries. A gamete has 23 single chromosomes, which is half a set. It is the zygote, and the body cells that grow from it, that have 46: two copies of each chromosome, one from each parent.

🧠

Memory hook

Halve it, join it, same again: 46 becomes 23 + 23, which becomes 46.

✓

Check yourself

A human zygote has 46 chromosomes. How many came from the egg, and why can't the sperm carry 46 too? (23 from each. A 46-chromosome sperm would give the zygote more than 46.)

Flashcards

(14)
What is a gamete?
A sex cell. The sperm cell is the male gamete (made by males) and the egg cell is the female gamete (made by females).
How much of the parent's genetic material does each gamete carry?
Half. That is why half of a baby's genetic material comes from each parent.
How many chromosomes are in a human gamete?
23 chromosomes.
How many chromosomes are in a human zygote, and in the cells of a human adult?
46 chromosomes in each.
What is DNA, and where is it kept?
A long chemical molecule that codes the genetic information. It is packaged into chromosomes, and the chromosomes are stored in the nucleus.
What is fertilisation?
When the nucleus of a sperm cell fuses with the nucleus of an egg cell, giving a new nucleus and forming a zygote.
Where does fertilisation happen?
In a fallopian tube, not in the uterus. It can only happen before the egg cell reaches the uterus.
What happens to the sperm cell when it enters the egg?
It loses its tail, and its nucleus then fuses with the egg's nucleus.
What is a zygote?
A fertilised egg cell. It is the offspring of both parents, the first stage of the life cycle, and it has a full set of genetic material.
What is an embryo?
The ball of cells formed when the zygote divides. It moves down the fallopian tube towards the uterus.
What are the stages after fertilisation, in order?
Zygote, embryo, foetus, baby.
In the human life cycle, what is reproduction and what is growth?
Reproduction is the step from adult to zygote. Every stage after that (zygote, embryo, foetus, baby, child, adolescent, adult) is growth, which is making new cells.
What rule links the chromosome numbers of parents, gametes and offspring?
Gametes have half the parent's number of chromosomes. Offspring have the same number as their parents.
Does a species with more chromosomes count as more complicated?
No. Different species have different numbers of chromosomes, and the number is not related to how complicated the species is.

Tap any card to flip it, or use Study as deck to go through them one at a time. In the full lesson these run as a spaced-repetition deck — you rate each card Hard, Good or Easy and the tricky ones keep coming back until they stick.

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How this lesson was checked. This KS3 Biologylesson was published through Lightbulb Learning's human-designed editorial process — the educational standards, accuracy rules and publication checks it must pass were authored and approved by Philip Halpin. It passed subject-specific assessment, automated educational checks and technical publication verification before going live (publication checks completed 2 October 2026). Published pages are monitored, human spot-checking is ongoing across the lesson library, and anything found wrong is corrected or withdrawn. How our lessons are made and checked. Spotted a mistake? Email hello@lightbulblearning.co and we'll review it.